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Breast Cancer:

BRCA-1 and BRCA-2(Breast Cancer Gene 1 and Breast Cancer Gene 2)

BRCA-1 and BRCA-2 are two tumor suppressor genes . Normally, these genes help prevent cancer by producing proteins that suppress abnormal cell growth. Certain changes (mutation) in these genes are linked mainly with hereditary breast and ovarian cacers .

According to the American Cancer Society (ACS), about 200,000 women are diagnosed with invasive breast cancer each year and about 20,000 with ovarian cancer. Of these cancers, about 5% to 10% will be due to a harmful mutation in BRCA-1 or BRCA-2 genes. Men can also inherit an increased risk of developing breast cancer, occasionally from mutations in BRCA-1, but primarily from mutations in the BRCA-2 gene

The test used to
To assess the risk of developing breast orovarian cancer associated with inheriting mutations in the BRCA-1 or BRCA-2 genes

سرطان الثدى


BRCA - 1 و 2 - BRCA

هما نوعان من الجينات المسيطرة على الورم. هذه الجينات تساعد على منع السرطان من خلال انتاج البروتينات التي تسيطر على نمو الخلايا غير الطبيعية. وترتبط بعض التغيرات (الطفرات) في هذه الجينات أساسا بسرطان الثدي وسرطان المبيض

ويستخدم هذا الاختبار ل

لتقييم مخاطر الاصابة بسرطان الثدي او المبيض

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