Cerebrospinal fluid analysis (CSF):
Cerebrospinal fluid (CSF) is a clear watery liquid filtrate that is formed and secreted by the choroid plexus, special tissue that has many blood vessels and lines the small cavities or chambers (ventricles) in the brain. CSF flows around the brain and spinal cord, surrounding and protecting them.
It is continually produced, circulated, and then absorbed into the blood system. About 500 mL is produced each day. This rate of production means that all of the CSF is replaced every few hours.
this test used to
disease or condition affecting the central nervous system (CNS) such as bleeding within the brain or skull, cancer, autoimmune disorder or infection
the way of sample obtaining
A sample of cerebrospinal fluid is collected by a doctor from the lower back using a procedure called a lumbar puncture or spinal tap.
CNS symptoms
infections and inflammation in the meninges or the brain (called encephalitis) can disrupt the blood-brain barrier and allow white and red blood cells and increased amounts of protein into the CSF. Meningitis and encephalitis can also lead to the production of antibodies. Immune diseases that affect the CNS, such as Guillain-Barré Syndrome, and multiple sclerosis can also produce antibodies that can be found in the CSF. Cancers such as leukemia can lead to an increase in CSF white blood cells (WBCs), and cancerous tumors can result in the presence of abnormal cells.
Analysis is requested:
CSF color, clarity and pressure during collection, CSF protein ,CSF glucose ,CSF cell count and CSF differential
السائل النخاعى
السائل النخاعى هو سائل مائى يتم انتاجه داخل الضفيرة المشيمية وايضا فى الانسجة المحتوية على اوعية دموية كثيرة وينتج ايضا داخل تجاويف المخ وهو يتواجد حول المخ والحبل الشوكى للاحاطة بهم وحمايتهم ويتم انتاج حوالى 500 مل كل يوم .
هذا الاختبار يستخدم ل
تشخيص حالة الجهاز العصبي المركزي مثل نزيف المخ و الجمجمة ، والسرطان ، والاضطرابات المناعة أو العدوى
طريق الحصول على عينة
ويتم جمع عينة من النخاعى من قبل الطبيب حيث يجمعها من أسفل الظهر باستخدام إجراء يسمى إجراء تراكم البزل أو في العمود الفقري السائل
ومن اعراض الاصابة بامراض الجهاز العصبى المركزى
الالتهاب السحائى والتهابات المخ
وزيادة كميات من البروتين في السائل النخاعي.الالتهاب السحائى والتهاب المخ يمكن أن يؤدي أيضا إلى إنتاج الأجسام المضادة
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