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Bone Marrow Aspiration and Biopsy:

Bone marrow aspiration and biopsy are procedures used to collect and evaluate bone marrow. Bone marrow is a soft fatty tissue found inside the body’s larger bones.

It has a honeycomb or sponge-like structure, consisting of a fibrous network that is filled with liquid. The liquid contains stem cells, blood cells in various stages of maturation, and “raw materials” such as iron, vitamin B12, and folate that are required for cell production.

A bone marrow aspirate collects a liquid sample of cells that can be studied individually. A biopsy collects a cylindrical core sample that preserves the marrow’s structure. The biopsy shows the relationships of bone marrow cells to one another and the overall cellularity – the ratio of marrow cells to fat and other constituents present in the sample.

Red blood cells (RBCs), platelets, and five different types of white blood cells (WBCs) are produced in the marrow as needed, with the number and type of cell being produced at any one time based on the use of cells, loss, and a continual replacement of old cells. For instance, RBCs, which carry oxygen throughout the body, have a lifespan of about 120 days.

The marrow paces RBC production at such a rate as to replace old RBCs that are taken out of circulation and maintain a relatively constant number in the blood.

The test used to

evaluate the type, quantity, and maturity levels of the blood cells present in the marrow; to evaluate the fibrous structure of the marrow; and sometimes to collect a sample of marrow for more specific testing

the way of sample obtaining

A bone marrow sample collected primarily from the hip bone (pelvis); sometimes collected from the sternum in adults or the tibia (shin bone) in infants

نخاع العظام

نخاع العظام هو نسيج دهنى لين يوجد داخل عظام الجسم وهو يشبه الاسفنج ويتكون من مجموعة من الالياف داخل سائل هذا السائل يحتوى على الخلايا الجذعية ويحتوى ايضا على:

عنصر الحديد وفيتامين
B12
وحمض الفوليك

يتم إنتاج خلايا الدم الحمراء (كرات الدم الحمراء) ،و الصفائح الدموية ، وخمسة أنواع مختلفة من خلايا الدم البيضاء
فى نخاع العظام والذى ينتجها كل 120 يوم

هذا الاختبار يستخدم ل
تقييم نوع وكمية ، ومستويات نضج خلايا الدم الموجودة في النخاع العظمي
طريق الحصول على عينة
جمعت عينة نخاع العظم في المقام الأول من عظم الفخذ (الحوض) ، التي تم جمعها في بعض الأحيان من القص عند البالغين أو الساق (عظم الساق) عند الرضع

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