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This test measures the amount of ferritin in the blood.
Ferritin is an iron-containing protien that is the primary form of iron stored inside of cells. The small quantity of ferritin that is released into the blood is a reflection of the amount of total iron stored in the body.
In healthy people, about 70% of the iron absorbed by the body is incorporated into the hemoglobin of red blood cells. Most of the remaining 30% is stored as ferritin or as hemosiderin , a complex of iron, proteins, and other materials. Ferritin and hemosiderin are present primarily in the liver but also in the bon marrow , spleen, and skeletal muscles.
Ferritin levels decrease in case of
- insufficient iron intake
-increased need for iron such as pregnancy, chronic blood loss and anemia
Ferritin levels increase
when more iron is absorbed than the body needs. Chronic absorption of excess iron will lead to the building of iron compounds in tissues and organs and may eventually cause their dysfunction and failure. This happens in hemochromatosis , a genetic disease in which increase body absorbance of iron.
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