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Adrenocorticotrophic Hormone Aldosterone (ACTH):

This test measures the amount of adrenocorticotropic hormone (ACTH) in the blood.

ACTH is a hormone that stimulates the production of cortisol. Cortisol is a steroid hormone important for regulating glucose, protein, and lipid metabolism, suppressing the immune system's response, and maintaining blood pressure.

Normally, ACTH levels increase when cortisol is low and fall when cortisol is high.
ACTH is produced by the pituitary gland . located below the brain in the center of the head, the pituitary gland is part of the endocrine system, a network of glands that work together to produce hormones that act on organs, tissues, and other glands to regulate systems throughout the body.

When cortisol levels fall in the blood, the hypothalamus produces corticotropin-releasing hormone (CRH). This stimulates the production of ACTH by the pituitary, which in turn stimulates the production of cortisol by the adrenal gland , small organs located at the top of each kidney.

the test used to

diagnose adrenal and pituitary diseases such as Cushing’s syndrome, Cushing’s disease, Addison’s disease, adrenal tumors, and pituitary tumors

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